The 18th verse declares that "the third part
of men" are slain by these horsemen.

The Great and Notable Day of the Lord is a
time of dealing with the human race. Only
a remnant [portion] will be left to go into
the Millennium [a thousand year reign of
Jesus Christ].

Only eight survived the Flood; there will be
more remaining here when the judgment
is completed, but it is true that the wicked
are to be rooted out of the earth.

"The inhabitants of the earth are burned
and few men are left." Isaiah 24:6