First Vial
Boils
Revelation 16:1-2

"And I heard a great voice out of the Temple saying to the Seven Angels, go your ways and pour out the Vials of the Wrath of God upon the earth.
And the first went and poured out his Vial upon the earth: and there fell a noisome and grievous sore upon the men which had the Mark of the Beast, and upon them which worshipped his image."